The product is based on recombinant human collagen (Rh Collagen) combined with hyaluronic acid and carboxymethylcellulose, developed to stimulate fibroblast activity and promote natural collagen regeneration.
CE certified medical device, manufactured according to European quality and safety standards.
Product Range / Variants
Bioactive Anti‑Age Serum
DAILY SERUM
Ideal home treatment to maintain results achieved with KARISMA Rh Collagen® injection. Acts on increasing fibroblast proliferation, reducing cell duplication time, and reducing oxidative stress, counteracting overall skin aging
Bioactive Cream
DAILY CREAM
Essential component of the home treatment, enhancing the effects of both the anti‑aging serum and the KARISMA Rh Collagen® injection treatment. Formulated to nourish and protect the skin throughout the day.
Natural Kernels Scrub System
PRE‑TREATMENT
Optimal evening pre‑treatment before applying the serum and cream. Exfoliation occurs on two levels: mechanical (fruit stone granules) and chemical (AHAs absorbed on the granules).
Complete Skin Care Set
FULL ROUTINE
Complete cosmetic line set at an advantageous price. The box contains all three references of the line.
Science & Composition
Recombinant Human Collagen Technology
KARISMA Rh Collagen® is based on recombinant human collagen (Type I), produced through advanced bioengineering processes. This technology ensures high biocompatibility, purity, and structural similarity to natural human collagen, supporting dermal regeneration and long-term skin quality improvement.
Triple-Action Biostimulation
The formulation combines: – Recombinant Human Collagen (Rh Collagen): stimulates fibroblast activity and promotes natural collagen synthesis. – Hyaluronic Acid (HA): provides hydration and improves dermal elasticity. – Carboxymethylcellulose (CMC): enhances structural support and product stability. This synergistic composition helps restore skin density, elasticity, and firmness.
Regulatory & Safety
KARISMA Rh Collagen® is a CE-certified medical device, manufactured according to European regulatory standards and strict quality control processes. The product is designed for high safety, optimal tissue integration, and predictable aesthetic outcomes.
Skin Density
Elasticity & Firmness
Hydration
Collagen Stimulation
Before & After Cases
Real transformations. Proven clinical results.
BEFORE
AFTER
Perioral Wrinkles
Reduction of fine lines and improvement of skin density with KARISMA Rh Collagen®
BEFORE
AFTER
Lower Face Rejuvenation
Improvement of skin firmness and texture with KARISMA Rh Collagen®
BEFORE
AFTER
BEFORE
AFTER
Download & Resources
Product Brochure
PDF
Product Brochure
PDF
Product Brochure
PDF
Product Brochure
PDF
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April 24
13:00 PM
Frontera Academy
Where Innovation Meets Clinical Excellence
Préime Dermofacial & Dermaceutical Experience
Discover the future of skin treatments, where technology meets performance. A new era of intelligent, data-driven aesthetics.